Archive for the 'Health' Category

PBPK Finite dose of barium part 1

After being busy with my theses now I am able to back to here again. Previous posts have explained the single time dose of a toxic chemical entering the ingestion tract. So this time, I would like to explain about the finite dose of barium that enters the body. As we know on the previous post, the single dose is described and the dose, and now the dose is continously enters the body or digestion organs. Read the rest of this entry »

Physiologically based pharmacokinetics example part 4

This post relates to previous post about biotransfer factor in previous post. If you haven’t visited that post yet, I suggest you do so. I would like to provide an example on how to calculate the concentration of chemical A if not 100% is removed in the liver organ.

The keyproblem to this matter is whether BTF is dependent or independent for chemical removal in the liver or not. Depends or independent is determined by toxicology study. We can know only if the figure is confirmed as a linear function between concentration of chemical in the body with the dose as follows: Read the rest of this entry »

Risk, health and insurance

We have talked the principle idea of risk assessment. In this post, I would like to again remind, that no one in this entire planet is risk-free for health problem. That is because we are actually get exposed with so many toxic chemicals present ambient within our surrounding. The inside process on how these toxic chemicals enter the body and get absorbed by our digestive tract is explained by toxicology science. Risk assessment only try to predict the estimation of people get an observable effect. Read the rest of this entry »

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